Launch of “Targeted Microbiome Profiling”, a pathway-based microbiome profiling service for health and disease.

TenWise BV and Predica Diagnostics BV have developed the “Targeted Microbiome Profiling (TMP)” service on the basis of the financial support from the Dutch RVO (MIT-R&D-samenwerkingsproject). The service allows faster profiling of the microbiome community as well as getting understanding of which biological pathways impact the functionality of the microbiome of interest, based on extracted RNA from samples from different microbiome niches. TMP uses ciRNAseq, Predica’s disruptive, high throughput targeted RNA sequencing technology in combination with TenWise’s expertise on literature mining, artificial intelligence and algorithm development, to detect biological pathways associated with health and disease. This combination gives researchers a full interpretation of composition and functional data within a few weeks hereby dramatically shortening timelines of sequencing and bio-informatics analyses within the industry. Also, it allows medical doctors to quickly evaluate results of individual patients for whom a rapid diagnosis is essential.

Relevant disease indications include inflammatory bowel disease (IBD), oncology and CNS diseases that have a suspected relation to the microbiome.

Please contact us for more information, and how our unique collaboration can help you with taking your microbiome profile data to a higher level.

Predica Diagnostics B.V is a spinoff from the Radboudumc, active in the field of diagnostics, prognostics and prediction of treatment response in oncology. Predica Diagnostics aims to bring its ciRNAseq technology to patients in 1 to 2 years with a first focus on developing the CervicaDX test. This test allows non-invasive detection of cervical abnormalities in women who are at risk of developing cervical cancer, with unprecedented specificity. This, and other diagnostic tests for host-microbiome interactions will improve diagnosis, prognosis prediction and produce a list of potentially successful precision medicines, thus aiding in development of personalized treatment plans for cancer patients.

Contact: www.predica-diagnostics.com, Marco de Boer CEO, (marco.deboer@predicadx.com)

TenWise B.V. offers text mining solutions that help researchers and medical professionals to extract knowledge from literature in a fast and effective way. Also, it collaborates within consortia of industry and academia in life sciences on artificial intelligence solutions that assist in drug discovery with a special focus on interventions in the microbiome. The company is based at Leiden Bio Science Park, the Netherlands and works for clients around the world.

Contact: www.tenwise.nl, Nils Hijlkema CCO (nils.hijlkema@tenwise.nl)

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